2022 MCS Annual Meeting Sessions

Held at Experiemntal Biology 2022, April 2-5, Philadelphia Convention Center

Saturday, April 2

9:30 AM - 11:30 AM, Room 201C

The Microcirculatory Society President's Symposium – Spotlight on the Microcirculation for Improving Health

Chairs: Jerome W. Breslin (University of South Florida) and Walter Lee Murfee (University of Florida)
  • Microvascular Oxygen Delivery and Hemodynamic Monitoring in the ICU - Asher Mendelson (Max Rady College of Medicine, University of Manitoba)
  • The role of gastrointestinal hormones in the metabolic control of endothelial function - Elena Osto (Institute of Clinical Chemistry, University of Zurich and University Hospital Zurich)
  • The impact of the endothelial glycocalyx on septic coagulopathy in mice and humans - Eric Schmidt (Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine)
  • Autoregulatory failure contributes to hypoperfusion in response to spreading depolarization - Eszter Farkas (Department of Cell Biology and Molecular Medicine, Albert Szent-Györgyi Medical School, University of Szeged)
  • Tissue-nonspecific alkaline phosphatase preserves cerebrovascular integrity in sepsis - Candice Brown (Department of Neuroscience, West Virginia University School of Medicine)

 

1:00 PM - 3:00 PM, Room 201C

Emerging Topics in the Microcirculation

Chairs: Erika Boerman (University of Missouri) and Brant Isakson (University of Virginia)
  • Introduction - Erika Boerman (Medical Pharmacology and Physiology, University of Missouri)
  • Novel Mechanisms of Autophagy-mediated Vasculoprotection - Cameron McCarthy (Cardiovascular Translational Research Center, Department of Cell Biology and Anatomy, University of South Carolina)
  • Loss of the Smooth-muscle-cell-Angiotensin II-Sensitive (SAS) lncRNA Triggers VSMC Hypertrophy and Cell Cycle Arrest: Application to Hypertension and Aortic Stiffness - Cristina Espinosa-Diez  (Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh)
  • Accelerated Vascular Aging Induced by the Common Chemotherapeutic Agent Doxorubicin: Understanding Underlying Mechanisms in Order to Inform Future Therapeutic Strategies - Zachary Stephen Clayton (Department of Integrative Physiology, University of Colorado Boulder)
  • Female Sex Protects Cerebral Arteries from Mitochondrial Depolarization during Acute Oxidative Stress - Charles Elbert Norton (Medical Pharmacology and Physiology, University of Missouri)
  • Piezo1 is a Mechanosensor Ion Channel in CNS Capillaries - Osama Harraz (Pharmacology, University of Vermont)
  • Vascular Mitochondria in Brain Aging - Ibolya Rutkai (Pharmacology, Tulane University)
  • Role of TFEB as Regulator of Autophagy Induced Changes in Endothelial Cells in T2DM - Bill Hughes (Cardiovascular Center, Medical College of Wisconsin)
  • Loss of Foxo1 Promotes the Growth of New Lymphatic Valves - Ying Yang (Molecular Pharmacology and Physiology, University of South Florida)
  • Closing Remarks - Brant Isakson (Robert M. Berne Cardiovascular Research Center, University of Virginia)

 

3:30 PM - 5:30 PM, Room 201C

Microcirculation in Organ Dysfunction

Chairs: Andreas M. Beyer (Medical College of Wisconsin) and Lauren Biwer (Tufts University School of Medicine)
  • Introduction - Andreas M. Beyer (Department of Medicine; Cardiovascular Center, Medical College of Wisconsin)
  • Neurovascular and Retino-Vascular Changes in Animal Models of Pregnancy Disorders - Junie P. Warrington (Neurology, University of Mississippi Medical Center) 
  • The Kynurenine Pathway and PDE Inhibition as potential druggable targets to treat Placental Microvascular Dysfunction in Preeclampsia - Michelle Broekhuizen (Neonatology, Erasmus University Rotterdam) 
  • Abstract 1: Pressure Modulation of Vacular L-Type Calcium Channels: Impliations in the Myogenic Response - Galina Mironova (University of Western Ontario)
  • Abstract 2: Differences in Cellular Metabolism and Metabolic Regulation between Non-diabetic and Diabetic Human Coronary Artery Endothelial Cells - Cynthia Xu (Cardiovascular Research Center, Rhode Island Hospital, Brown University) 
  • Abstract 3: Incorporation of Tumor Spheroids into an Ex-vivo Tissue Culture Model for Investigating Cancer Cell–Microvascular Interactions - Arinola Lampejo (Biomedical Engineering, University of Florida)
  • Soluble Protein Oligomers, Endoplasmic Reticulum Stress and Vascular Dysfunction - Emily Waigi (Cell Biology & Anatomy, University of South Carolina)
  • White Matter Penetrating Arteriole Dysfunction in Patients with Alzheimer's Disease - Katie Ann Fopiano (Physiology, Augusta University)

 

6:00 PM - 8:00 PM, Terrace 1

MCS President's Poster Reception and Business Meeting

This meeting will feature receipients of the Zweifach student and Pappenheimer postdoctoral awards, plus award presentations and updates about the MCS.

 

 

Sunday, April 3

1:30 PM - 3:00 PM, Room 201C

MCS Landis Award Lecture: Microcirculatory Networks

Timothy W. Secomb (Department of Physiology, University of Arizona)

 

Monday, April 4

3:30 PM - 5:00 PM, Room 201C

Gabor Kaley Award Featured Topic (APS/MCS Joint Award): Lymphatic Function and Tissue Homeostasis

David Zawieja (Department of Medical Physiology, Texas A&M University)
Also featuring presentations of abstacts by:
  • David Small, Cornell University
  • Melissa Luse, University of Virginia
  • Jorge Castorena-Gonzalez, Tulane University
  • Scott Zawieja, University of Missouri

 

Posters

Presentations are from 10:15-12:15 on Sunday and Monday. The MCS posters include the following abstract categories:
1030-APS    Angiogenesis/Microvascular Remodeling/Injury & Repair
1031-APS Atherosclerosis/Thrombosis/Platelets
1032-APS Inflammation/Leukocyte-Endothelium Interactions
1033-APS Instrumentation, Methodology, and Experimental Models
1034-APS Ischemia-Reperfusion/Free Radical Biology
1035-APS Lymphatic Function
1036-APS Microvascular Cell Signaling Pathways
1037-APS Microvascular Development and Aging
1038-APS Microvascular Flow Regulation/Oxygen Delivery/Networks
1039-APS Microvascular Mechanics/Hemodynamics/Rheology
1040-APS Microvascular Pathophysiology-pharmacology, Therapeutics and Translational Aspects
1041-APS Pericytes and Stem Cells
1042-APS Permeability/Fluid & Solute Exchange/Glycocalyx
1043-APS Tissue-Microvessel Interactions/Extracellular Matrix
1044-APS Vasomotor Control: Endothelium/Smooth Muscle/Nerves