The Microcirculatory Society Annual Meeting at Experimental Biology 2017

April 22-26, 2017 - Chicago

SATURDAY, APRIL 22

 

MICROCIRCULATORY SOCIETY PRESIDENT’S SYMPOSIUM: (NOT) LOST IN TRANSLATION: BRIDGING THE GAPS BETWEEN MICROCIRCULATORY BASIC SCIENCE AND CLINICAL SCIENCE

Symposium

Sat. 9:30 am— M cCormick Place Convention Center, W196B

Chaired: W.M. Chilian and R.E. Rumbaut

9:30 Microcirculation from Bench to Bedside and Beyond: Whither NHLBI? George Mensah. National Institutes of Health.

10:00 Mechanisms of Vasomotor Control in Humans Change during Aging and Disease. David Gutterman. Medical

College of Wisconsin.

10:30 Molecular Programming of Arteries and Veins in Health and Disease: The Power of Mouse Genetic

Approaches. Rong Wang. University of California- San Francisco.

11:00 Clinical Trials Need to Reflect Underlying Physiology: The Experience with Stable Ischemic Heart Disease.

William Weintraub. Christiana Care Health System.

 

DEPRESSION AND ITS EFFECTS ON MICROVASCULAR FUNCTION AND

VASCULAR ADAPTATION

Symposium

Sat. 1:00 pm— M cCormick Place Convention Center, W196B

Chaired: P. Chantler and M. Olfert

1:00 Interventional Approaches to Determining Links between Chronic Depression and Microvascular Dysfunction.

Jefferson Frisbee. Univ. of Western Ontario.

1:30 Interaction of Obesity and Nrf2 Deficiency Accelerates Cerebromicrovascular Aging and Impairs

Neurovascular Coupling Responses. M.N. Valcarcel- Ares, S. Tarantini, P. Hertelendy, Z. Tucsek, T.

Gautam, T. Kiss, R. De Cabo, E. Farkas, Kinter, W. Sonntag, A. Csiszar, Z. Ungvari. University of Oklahoma Health Sciences Center—Reynolds Oklahoma Center on Aging Research, NIA, University of Szeged, Hungary and Oklahoma Medical Reseach Foundation.

1:45 Stress and Depression: Its Role on Cerebral Vascular Dysfunction. Paul Chantler. West Virginia Univ. Sch. of Med.

2:15 Exercise Recovers Loss of Microvessel Density due to Lowered Nitric Oxide Bioavailability. K. Branyan,

M. Ashman, C. Pitzer, P. Chantler, M. Olfert. West Virginia University.

2:30 Effects of Obesity and Depression on Microvascular Angiogenesis. Mark Olfert. West Virginia Univ. Sch. of Med.

 

INVESTIGATING MICROVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY USING NOVEL TECHNIQUES

Symposium

Sat. 3:30 pm— M cCormick Place Convention Center, W192B

Chaired: K.Y. Stokes and F.N. Gavins

3:30 Introduction by the Chairs.

3:35 Using the Zebrafish to Dissect Vascular and Lymphatic Development. Nathan Lawson. Univ. of

Massachusetts Med. Sch.

4:05 An Ischemia Model on a Chip. W. Yin, L. Abejar, D.A. Rubenstein, M.D. Frame. Stony Brook University.

4:30 Microvascular Perfusion Heterogeneity Impairs Oxygenation and Contributes to Peripheral Vascular Disease in Metabolic Syndrome. P. McClatchey, F. Woo, I. Olfert, C. Eliis, D. Goldman, J. Reusch, J. Frisbee. University of Colorado, Novartis, West Virginia University and University of Western Ontario, Canada.

4:35 Novel Approaches to Manipulate Gene Expression in the Mouse Kidney: siRNA Silencing and Gene Rescue. L.D. Asico, P. Konkalmatt, V.M. Villar, X.Wang, I. Armando, H. Lin, P.A. Jose. The George Washington University School of Medicine and Health Sciences.

4:50 A Network Approach to Studying Skeletal Muscle Blood Flow Control: The Whole is Greater than the

Sum of Its Parts. Dwayne Jackson. Western Univ., London, Ontario.

5:20 Closing Remarks by the Chairs.

 

MCS POSTER RECEPTION

Poster Discussion

Sat. 6:00 pm— M cCormick Place Convention Center, W196B

 

SUNDAY, APRIL 23

 

MCS LANDIS AWARD LECTURE

Sun. 3:15 pm— M cCormick Place Convention Center, W196B

Chaired: J. Loffing and H. Cai

3:15 Leukocyte Integrin Activation under Flow. Klaus Ley. La

Jolla Inst. for Allergy and Immunology

 

MCS BUSINESS MEETING

Sun. 4:30 pm— M cCormick Place Convention Center, W196B

 

TUESDAY, APRIL 24

 

KALEY LECTURE FEATURED TOPIC: THE COMPLICATIONS OF DIABETES AND THE

ROLE OF INFLAMMATION: MECHANISMS AND THERAPEUTIC OPPORTUNITIES

Tue. 10:30 am— M cCormick Place Convention Center, W190B

Chaired: A.M. Schmidt

10:30 RAGE Signal Transduction Mediates Chronic Inflammation in Obesity, Diabetes and its Complication: Mechanisms and Therapeutic Opportunities. Ann Marie Schmidt. New York Univ. Med. Col.

11:30 Smooth Muscle Cells Are the Source of Heart Failure-Causing Methylglyoxal in Diabetes Mellitus. K.R. Bidasee, F. Alomar, R. Fang, J.L. Cox, G.J. Rozanski, J. Singh. University of Nebraska Medical Center, University of Dammam, Saudi Arabia, Shandong University School of Medicine, People’s Republic of China, and University of Central Lancashire, United Kingdom.

11:45 Leptin Replacement Therapy Restores Endothelial Function in Mouse Models of Congenital and Acquired Lipodystrophy by Reducing NOX-1 and NOX-4-Derived Reactive Oxygen Species. T. Bruderdo Nascimento, S. Kennard, W. Chen, E.J. Belin de Chantemèle. Augusta University.

12:00 Myeloid-Derived Suppressor Cells in Adipose Tissue Homeostasis. K.B. Stivers, P. Chilton, J. Beare, J. Dale, C.L. Kaufman, J.B. Hoying. Cardiovascular Innovation Institute, University of Louisville and Christine M Kleinert Institute.

12:15 Exercise Reverses Metabolic Syndrome Perivascular Adipose Tissue Impairment of Aortic Relaxation. E. DeVallance, K. Branyan, K. Lemaster, S. Clayton, C. Killmer, J. Frisbee, P. Chantler. West Virginia

University and Western University, Canada.